CADA7: High resolution Magnetic Resonance Imaging in a monogenic model of cerebral small vessel disease
CADA7 is a prospective 7 Tesla MRI study. In this study, we aim to assess microstructural and morphological modifications of cerebral cortex in CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy), a monogenic model of cerebral small vessel disease.
Hereditary diseases of the small cerebral arteries of unknown cause
Hereditary diseases of the small cerebral arteries of unknown cause. Identification of the genes involved using a "gene candidate" approach focusing on the Notch3 signaling path and a "reverse genetics" approach.
Programme of research into Episodic Type 2 ataxia
Molecular exploration of patients suffering from episodic Type 2 ataxia without any punctual mutation identified in CACNA1A: search for major rearrangements.